Pharmaceutical Water FiltrationFlier’s Quality Water Systems provides industry-leading pharmaceutical water filtration solutions backed by custom preventive maintenance programs and 24/7 troubleshooting support.
We offer both standard and application-specific systems designed to meet the industry’s highest standards for:
Quality
Throughput
Return on Investment (ROI)
Our USP- and FDA-compliant water treatment solutions deliver ultrapure water for:
Pharmaceutical production
Water for Injection (WFI)
Hemodialysis
Other medical and healthcare applications
Our systems are designed to help pharmaceutical manufacturers meet strict regulatory requirements with confidence.
Benefits include:
Precise filtration, measurement, and process control
Improved regulatory compliance
Comprehensive documentation to support inspections and audits
Maintain reliable production with stable water quality throughout your operations.
Advantages include:
Consistent supply volume and water purity
Improved manufacturing efficiency
Reduced process variability
High-purity water supports consistent product quality at every stage of production.
Key benefits include:
Lower product rejection rates
Reduced cost per acceptable unit
Higher overall product quality assurance
Improved batch-to-batch consistency
Our pharmaceutical water systems help lower long-term operational expenses.
Benefits include:
Increased equipment uptime
Reduced planned and unplanned maintenance
Lower water consumption
Reduced utility costs
For many years, Flier’s Quality Water Systems has designed, engineered, and installed advanced pharmaceutical water filtration systems across North America.
We help pharmaceutical manufacturers, compounding pharmacies, and biotechnology companies meet Water Code requirements established by FDA 21 CFR Part 211 and the United States Pharmacopeia (USP).
Our systems are engineered using validated purification technologies, including:
Reverse Osmosis (RO)
Electrodeionization (EDI)
UV Disinfection
These technologies produce:
Purified Water (PW)
Water for Injection (WFI)
Other pharmaceutical-grade water tailored to your production requirements
Good Manufacturing Practice (GMP)-supported resin regeneration facility
Legally operated in Byron Center, Michigan, USA
Around-the-clock emergency service
Rapid response to minimise pharmaceutical production downtime
Comprehensive documentation includes:
Installation Qualification (IQ)
Operational Qualification (OQ)
Performance Qualification (PQ)
These documents support audit readiness and ongoing regulatory compliance.
Custom-designed preventive maintenance plans
Tailored to meet your facility’s production requirements
Whether you’re upgrading an existing pharmaceutical water system or designing a new facility from the ground up, Flier’s delivers the engineering expertise, documentation, and regulatory knowledge needed for reliable, compliant pharmaceutical water treatment.
Water filtration for pharmaceutical applications is a highly specialised, multi-stage purification process that removes biological, chemical, and particulate contaminants.
The resulting water is produced to comply with United States Pharmacopeia (USP) and Food and Drug Administration (FDA) regulatory standards for pharmaceutical manufacturing.
Pharmaceutical water systems in the United States must comply with several key regulations, including:
USP <1231>
FDA 21 CFR Part 211
USP Water for Injection (WFI) Monograph (for sterile and parenteral drug production)
Meeting these standards helps ensure product quality, patient safety, and regulatory compliance.
Pharmaceutical water systems typically use multiple purification technologies to achieve the required level of water purity.
Common technologies include:
Reverse Osmosis (RO): Removes the majority of dissolved contaminants.
Electrodeionization (EDI): Provides final polishing for ultra-high-purity water.
UV Disinfection: Eliminates microbial contamination and reduces organic compounds.
Together, these technologies produce consistently high-quality pharmaceutical-grade water for critical manufacturing applications.
